منابع مشابه
Retinal Cell Biology IGFBP-3 and TNF-a Regulate Retinal Endothelial Cell Apoptosis
Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee Department of Neuroscience and Cell Biology, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, New Jersey Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee Cell Systems Corp., Kirkland, Washington Case Western Reserve University, Cleveland...
متن کاملAdiponectin alleviate blood hypercoagulability via inhibiting endothelial cell apoptosis induced by oxidative stress in septic rats
Objective(s): The purpose of this study was to detect the protective effects of adiponectin on coagulation dysfunction and its mechanism in sepsis of rats.Materials and Methods: The experimental samples were composed of sham group, model group that was underwent cecal ligation and puncture (CLP) and three adiponectin treatment groups that treated by adiponectin with different dose (72 μg/kg, ...
متن کاملThe role of pulsatile flow in controlling microvascular retinal endothelial and pericyte cell apoptosis and proliferation.
AIMS Aberrant retinal blood flow is a hallmark of various retinopathies and may be a causative factor in the pathology associated with these conditions. We examined the effects of pulsatile flow on bovine retinal endothelial cell (BREC) and bovine retinal pericyte (BRP) apoptosis and proliferation. METHODS AND RESULTS Co-cultured BRECs and BRPs were exposed to low (0.3 mL/min) or high (25 mL/...
متن کاملApoptosis regulates endothelial cell number and capillary vessel diameter but not vessel regression during retinal angiogenesis.
The growth of hierarchical blood vessel networks occurs by angiogenesis. During this process, new vessel growth is accompanied by the removal of redundant vessel segments by selective vessel regression ('pruning') and a reduction in endothelial cell (EC) density in order to establish an efficient, hierarchical network. EC apoptosis has long been recognised for its association with angiogenesis,...
متن کاملHyperoxia induces retinal vascular endothelial cell apoptosis through formation of peroxynitrite.
Hyperoxia exposure induces capillary endothelial cell apoptosis in the developing retina, leading to vaso-obliteration followed by proliferative retinopathy. Previous in vivo studies have shown that endothelial nitric oxide synthase (NOS3) and peroxynitrite are important mediators of the vaso-obliteration. Now we have investigated the relationship between hyperoxia, NOS3, peroxynitrite, and end...
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ژورنال
عنوان ژورنال: Apoptosis
سال: 2012
ISSN: 1360-8185,1573-675X
DOI: 10.1007/s10495-012-0777-3